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Microbeads
Anti-DC (OX62) MicroBeads, rat

Anti-DC (OX62) MicroBeads have been developed for the positive selection or depletion of OX62+ dendritic cells (DCs) from blood, lymphoid, and non-lymphoid tissue.

Quantity

Overview

Anti-DC (OX62) MicroBeads have been developed for the positive selection or depletion of OX62
+
 dendritic cells (DCs) from blood, lymphoid, and non-lymphoid tissue.

Detailed product information

Background information

The monoclonal antibody OX62 recognizes the integrin αE2 subunit (molecular mass: 150 kDa). OX62 is expressed on the
CD4
+
 and the CD4
-
 subset of dendritic cells but not on plasmacytoid dendritic cells in lymphoid tissue or on epidermal Langerhans cells. OX62 is also found on a subpopulation of epidermal TCRα/β
+
 or TCRγ/δ
+
 T cells and on a subset of folliculo-stellate-like (S100
+
) cells in the anterior pituitary. It is not expressed on macrophages.

Downstream applications

Isolated OX62
+
 dendritic cells were used, for example, for analysis of the differential phenotype, function, and migration of dendritic cell subsets.
1

Columns

For positive selection: MS, LS, XS, or autoMACS
®
 Columns. For depletion: LD, D, or autoMACS Columns.
  • 10e9 total cells : 0
  • Rat : 0
  • 2 mL : 0