HiGlutaXL™ medium contains the stabilised
dipeptide form of L-glutamine, L-alanyl-L-glutamine.
HiGlutaXL™ medium offers several advantages over
the conventional glutamine containing media. Dipeptide
form prevents the intramolecular cyclization reaction,
thus preventing toxic build-up of ammonia. L-alanyl-Lglutamine incorporates L-alanine that protects the alpha
amino acid group. Aminopeptidases within the cell break
the dipeptide, gradually releasing both L-glutamine and
L-alanine for use by the cell. The gradual release of Lglutamine obviates the need of addition of L-glutamine
at the time of use and allows liquid media to be stored at
4°C for longer periods.
AL047G is HiGlutaXL™ Minimum Essential Medium
Eagle with Earle's salts, L-alanyl-L-glutamine, sodium
bicarbonate and non-essential amino acids. Users are
advised to review the literature for recommendations
regarding medium supplementation and physiological
growth requirements specific for different cell lines.