µ Columns are especially designed for small-scale molecular biology and protein biochemistry applications. Prior to use, the µ Column is placed in a separator, which induces a strong magnetic field within the column. Molecules labeled with the extremely small MACS

 MicroBeads are retained on the column, whereas unlabeled material can be efficiently washed away. Additionally, enzymatic processing of retained molecules, such as cDNA synthesis, can be performed on the µ Column when placed in the thermoMACS™ Separator. Target molecules can be eluted in a small, convenient volume. Applications using µ Columns include mRNA isolation and cDNA synthesis, immunoprecipitation, purification of DNA and RNA binding proteins, protein interaction studies, or display technologies.