Microbeads
Anti-HLA-DR MicroBeads, human
Anti-HLA-DR MicroBeads have been developed for positive selection or depletion of antigen-presenting cells from PBMCs, cord blood, bone marrow, and tissue.
Quantity
The HLA-DR antigen is constitutively expressed on professional antigen-presenting cells (dendritic cells, B cells, monocytes/macrophages), and its expression is further up-regulated upon activation. On T cells, NK cells, hematopoietic precursor cells, and some epithelial cells the expression of HLA-DR is induced by cell activation.
Downstream applications
HLA-DR–positive cells are isolated, for example, for serological typing of HLA class II molecules or studies on antigen presentation.
Columns
For positive selection: MS, LS, XS, or autoMACS
®
Columns. For depletion: LD, D, or autoMACS Columns.