Background information
iNKT cells represent a distinct lymphocyte population, characterized by expression of an invariant T cell receptor α-chain and certain TCR β-chains (Vα24-Jα18 combined with Vβ11). iNKT cells are involved in immunoregulatory processes such as tolerance, host defense, and tumor surveillance.
Due to the nature of the antibody, a limited degree of pre-activation of target cells might occur after separation with this product.