In mice, CD138 (Syndecan-1) is expressed on pre-B and immature B lymphocytes in the bone marrow. It is lost when B cells emigrate into the periphery, is absent on circulating and peripheral B cells, and is re-expressed upon B cell differentiation into plasmablasts and plasma cells.
Applications
Enrichment of cells expressing mouse CD138 antigen, e.g. plasma cells from bone marrow and spleen.