Background information
The monoclonal antibody OX62 recognizes the integrin αE2 subunit (molecular mass: 150 kDa). OX62 is expressed on the
CD4
+
and the CD4
-
subset of dendritic cells but not on plasmacytoid dendritic cells in lymphoid tissue or on epidermal Langerhans cells. OX62 is also found on a subpopulation of epidermal TCRα/β
+
or TCRγ/δ
+
T cells and on a subset of folliculo-stellate-like (S100
+
) cells in the anterior pituitary. It is not expressed on macrophages.